Born in Nablus in 1897 to a well-known family of the city, Adel Zuwaiter completed both his elementary and high school educations in Beirut. He received his first degree in the Arts from the Sultan College in Constantinople. He was appointed as a reserve officer in the Ottoman Army in 1916, and soon after he defected with the Arab Revolt by joining the forces of the Arab Army led by Prince Faisal Bin Hussein. Because of this, he received a death sentence in absentia from the Turks in 1917.
He went to Cairo to continue to pursue his education but was interrupted by the British Mandate of Palestine and his subsequent return to Nablus. Adel Zuwaiter represented the city of Nablus (together with Mohammed Izzat Darwazeh and Ibrahim Abdul Hadi) at the First Syrian Convention in Damascus in 1919, in which the proclamation of the independence of Syria was announced. He contributed to the drafting of the first constitution of that era.
Following the French occupation of Damascus in 1920, Zuwaiter went to the School of Law in Paris, where he graduated in 1925. Simultaneously, he began working on translations of the great works of French literature. Then he returned to Palestine and worked as a lawyer in Nablus. He also became a teacher at the Law School in Jerusalem from 1927-36. He voluntarily represented political activists during the Revolts of 1929-1930 and 1933, and he also represented Nablus in most Palestinian national conferences. In 1928, he became a member of one of its first Arab Executive Committees.
In the 1950s, Zuwaiter resigned from teaching at the Law School and dedicated his efforts and career to translating over 36 volumes of famous universal thought (e.g., Montesquieu, Jean-Jacque Rousseau, Voltaire, Emil Ludwig, Gustave Lebon, etc.). He was elected as a member of the Iraqi Scientific Forum in 1953 and of the Arabic Language Forum in Damascus in 1955. He had a heart attack whilst translating the famous book Les Penseurs de l’Islam (The Philosophers of Islam) (5 vols.) by the French author Carra de Vaux and subsequently died on 21 November, 1957.